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Serie A Weekend Predictions

Once again we are back with the predictions for the upcoming Serie A matchweek. We are well into the 2nd part of the season as the teams will be playing their 25th matchweek. The title race in Serie A became even more complicated after Lazio defeated Inter in the last round. They are now the major contenders to strip Juventus of their title. Due to a match in the Champions League, Juventus will feature as early as possible. In this case, they are playing on Saturday afternoon in an away fixture against SPAL. Come Sunday, we have Genoa hosting Lazio in the early fixture. Last but not least, Inter are playing at home to Sampdoria as they are looking to bounce back with a victory right away. Below, you will find our weekly Serie A predictions.

SPAL vs Juventus >> click here for live odds

This is not the season SPAL were expected to have; however, they are stuck rock bottom on the table. As a matter of fact, they are 8 points behind the team that’s just outside of the relegation zone. Many experts had them pinned for a relegation battle but no one expected them to be playing this bad. SPAL have just 15 points after 24 matchweeks which is a record low for them. To make things worse, now they have to face the holding champions who can’t afford to drop points. However, there is one positive side in all of this for SPAL. Last year, they managed to defeat Juventus 2:1 in this fixture. The year before that, they held them to a draw. This means that Juventus have a hard time playing away to SPAL. If they rotate their squad for the UCL midweek, SPAL just might have a chance.

The holding champions returned to the top of the table thanks to Lazio defeating Inter last weekend. They can’t be dropping anymore points at this stage of the season, especially not to teams like SPAL. With Champions League action midweek, Juventus will be tempted to rotate part of their squad. Ronaldo didn’t play last week against Brescia so he should be leading the way on Saturday against SPAL. He is their number 1 scorer which means Juventus are dependent on his goals. Juventus have had problems when facing SPAL at their home ground. As a team, SPAL haven’t been part of the top flight for a long time which is why this will be only their 3rd home match against Juventus. However, so far they won one and drew the other one. The Champions need to travel there prepared for a tough match.


Juventus are considered absolute favorites to win this one. Even though they are not at their best and have an UCL match midweek, the difference in quality is rather vast. However, SPAL are desperate at the moment as they are bottom of the table. The least they could do is score a goal. For that reason, we are backing an Away Side Victory & Over 2.5 Goals.

Genoa vs Lazio >> click here for live odds

The hosts have been fighting relegation for most of the season. The last couple of weeks have been very good for them as they are slowly but surely climbing out of the relegation zone. They have won 8 out of the last 12 points and are just 1 point behind Sampdoria who are just above the relegation zone. It’s unlucky for them to be facing the strongest team in Serie A at the moment; however, that’s the schedule and they have to try and win every game. Last year, Genoa defeated Lazio 2:1 in this fixture and their fans will be hoping for a similar outcome. The team is playing good right now, especially in attack and they might have enough quality to surprise Lazio on Sunday.

The visitors are finally considered real title contenders. Last week they managed to win against Inter even though they went a goal behind. This means that Inter have now defeated both Inter and Juventus in the Serie A this season. They even have the best goals scored to goals conceded ratio out of all the teams in the Serie A. It has been a long time since Lazio was even in contention for a Scudetto; however this might be their year. Their attackers are in-form and their defense is solid. If they avoid major injuries, Lazio might be champions at the end of the season. There is a lot of football until then and first they need to defeat Genoa on Sunday. Last year they lost this fixture and will now try to make up for it.


Based on quality and performance, Lazio are favorites to win this fixture. However, Genoa are fighting relegation and they will try to win every home game they play until the rest of the season. Both sides can’t afford to drop any points right now which will add even more pressure. For that reason, we are backing Both Teams to Score.

Inter Milan vs Sampdoria >> click here for live odds

Conte’s men took a huge step back when they lost to Lazio in the last round. They are now 3rd on the table, 3 points away from 1st placed Juventus. They don’t really care about European matches this year which means they will be playing 1 game per week. Inter need to return to winning ways right away if they hope to be champions at the end of the season. Sampdoria are facing relegation so they shouldn’t be too much of a problem for Inter. They have won the last 5 fixtures against them and haven’t lost at home to Sampdoria since 2017. This season, Sampdoria are not nearly as good as they were in the previous couple of seasons. Inter should use that to their advantage and get all 3 points on Sunday.

When they defeated Torino two weeks ago it seemed Sampdoria are on their way out of relegation. However, last week’s massive loss to Fiorentina has put them just 1 point above the relegation zone. To make things worse, now they have to face Inter and if they lose chances are Sampdoria will be right back where they started. We need to go all the way back to 2017 to find the last time Sampdoria defeated Inter. However, that was a different time as Inter were struggling in every department and were even failing to finish the season in the TOP 4. This year things are much different and they already lost once to them in the reverse fixture. Inter is now playing at home which will make things even harder for Sampdoria.


It’s hard to look past Inter for this fixture. They have the quality and the need to get all 3 points on Sunday. Sampdoria have been really bad this season and it’s very unlikely that they can cause an upset against Inter. That’s why we are backing a – 1.75 Asian Handicap.

Full Serie A Round 25 Predictions >> click here for live odds

Above, we made predictions about the most exciting matches of the 25th Serie A round. However, we have to mention the rest of the games as well. Below, you can see our predictions for the rest of the fixtures.

  • Brescia vs Napoli – Away Side Victory
  • Bologna vs Udinese – Both Teams to Score
  • Fiorentina vs AC Milan – X2 Double Chance
  • Atalanta vs Sassuolo – Asian Handicap – 1.75
  • Torino vs Parma – X2 Double Chance
  • Hellas Verona vs Cagliari – Both Teams to Score
  • Roma vs Lecce – Home Side Victory

For more Serie A Predictions, tune in with us next week!

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