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Serie A Weekend Predictions

The 21st Serie A round is upon us and it will be one of the best so far in this season. The reason for that is because all the title chasers are playing tough, derby matches. After playing 2 draws in a row and surrendering the 1st place to Juventus, Inter will now face Cagliari who until several weeks ago were one of the best teams in the league. Later on Saturday, we have a city derby between Roma and Lazio which is one of the biggest rivalries in the Italian top flight. Last but not least, we have Juventus squaring off against the team that used to be their biggest contender in the last couple of years. However, Napoli have fallen on hard times and it’s hard to believe that they could surprise the holding Champions. Below, you will find our weekly Serie A predictions.

Inter Milan vs Cagliari >> click here for live odds

Conte’s side lost their hard earned advantage over Juventus in just 2 rounds. While the draw against Atalanta was no surprise, last week’s blunder against Lecce was a total shock for Inter fans. Two draws in a raw has seen Juventus create a 4 point advantage over them. Additionally, now they get to play against a side that was doing incredibly well until several weeks ago. It’s no surprise that Cagliari are 6th on the table and Inter will have to present a much better performance than the one against Lecce. Another slip-up could see them out of the title race because Juventus do know how to win this league.

Until a couple of weeks ago, Cagliari were one of the best teams in the league. They have been without a win in 6 Serie A round and they are still located in the TOP 6. That shows how good they were before this run of bad results. Facing Inter at this moment is not ideal for Cagliari; however, a positive result against a title chasing side might be what the team needs to boost moral and return to their previous state. Cagliari defeated Inter at their stadium back in 2016 but that was a much different Inter side. This season, they already lost to them in the reverse fixture. Additionally, they played each other in the Cup and Inter walked away with a 4:1 victory. Cagliari will have to improve a lot if they hope for a positive result.


Dropping points 3 games in a row will be a disaster for this Inter side. Quality wise, they are absolute favorites against Cagliari. Additionally, they do have home turf advantage as well. We expect Cagliari to put up a fight but Inter should be winning this one ultimately. For that reason, we are backing a Home Side Victory & Over 2.5 Goals outcome.

Roma vs Lazio >> click here for live odds

Here is a fixture that promises tons of excitement and a lot of drama as well. Roma and Lazio have one of the biggest rivalries in the league as they are both from the capital and they also share the stadium. This time Roma will be the home side; however, that won’t stop thousands of Lazio fans from attending the match. Roma went through tons of changes during the summer and no one expected them to be fighting for a TOP 4 spot this year. They are playing very good at the moment and a win over Lazio will certainly boost the morale of the squad. After two losses, Roma returned to winning ways against Genoa in the last round and they are ready to square off against Lazio.

This is the team that’s been surprising everyone this year. They were overlooked at the begining because everyone believed Juventus, Inter, Napoli, and Atalanta are the teams that should be watched. Lazio took their underdog status to another level as they defeated both Juventus and Napoli while they held Atalanta to a draw. With Inter slipping up in the last 2 rounds, Lazio are now just 2 points below them. With a win on Sunday and if a certain result goes their way, Lazio could go up to the 2nd position on the table. They are the 2nd highest team when it comes to scoring goals while their defense is also one of the best in the league. Their record against Roma is not very good but this is a much different Lazio side than in previous years.


Lazio are currently performing better and they also have more squad depth and quality. However, Roma are considered hosts here and they will do their best to win this fixture. Even the odds suggest that this is a hard fixture to predict as the odds for a home side or away side victory are very close. That’s why we are backing an Over 2.75 Goals outcome.

Napoli vs Juventus >> click here for live odds

In the last couple of seasons, this fixture was considered as a “title decider”. However, hard times have fallen over this Napoli side as they are not even close to how good they were last year. The internal problems destroyed the team and the coach change has done little to change that. They have just 1 win in the last 5 rounds and now have to host the table leaders. Napoli are currently 11th on the table with just 24 points after 20 rounds. However, they did manage to defeat Lazio in the cup midweek so maybe good times are coming for Napoli. Nevertheless, they haven’t defeated Juventus at home in Serie A since 2015. The reverse fixture this year ended with a 4:3 victory for Napoli so they will try to at least hold the champions to a draw on Sunday.

Coach Sarri is slowly but surely turning this Juventus squad into his own. He changed their tactical approach which was why Juventus were struggling to show dominance. However, it seems they adapted perfectly because at the moment they are defeating everyone and scoring several goals in the process. Ronaldo also found his form which will be a real boost for Juventus in the 2nd part of the season. Facing Napoli is always hard; however, the way they are performing right now is not showing any promise. Juventus should be able to get a win on Sunday and protect their 4 point lead on the top. They can’t slip up now because Inter are not going to give up on the title race. Every point that Juventus drops will go in their favor.


At the beginning of the season, we had a much different Napoli that played 10 times better than right now. However, even that wasn’t enough to defeat Juventus. Right now it’s Juventus who are in much better form while Napoli are struggling to get a win. For that reason, we are backing an Away Side Victory.

Full Serie A Round 21 Predictions >> click here for all Serie A Live Odds

Above, we made predictions about the most exciting matches of the 21st Serie A round. However, we have to mention the rest of the games as well. Below, you can see our predictions for the rest of the fixtures.

  • Spal vs Bologna – Both Teams to Score
  • Fiorentina vs Genoa – Home Side Victory
  • Torino vs Atalanta – Away Side Victory
  • Parma vs Udinese – Over 2.5 Goals
  • Hellas Verona vs Lecce – Both Teams to Score
  • Sampdoria vs Sassuolo – Home Side Victory

For more Serie A Predictions, tune in with us next week!

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